2. Signaling Pathways
  3. GPCR/G Protein
  4. Bombesin Receptor
  5. Bombesin Receptor Ligand

Bombesin Receptor Ligand

Bombesin Receptor Ligands (3):

Cat. No. Product Name Effect Purity
  • HY-P11768
    AMBA
    		Ligand
    AMBA is a gastrin-releasing peptide receptor (GRPR, BB2, BRS-2) ligand with a human IC50 of 0.82 nM and a human Ki of 0.65 nM. AMBA binds to GRPR with high specificity and high affinity, and undergoes receptor-mediated endocytosis, which retains the conjugated radiometal in target cells. AMBA is applicable for the research of prostate cancer.
  • HY-P10267
    Neuromedin (B-30)
    		Ligand
    Neuromedin B-30 is the neuropeptide, which is orignally isolated from porcine brain and spinal cord. , and may exhibit activity in stimulating smooth-muscle. Neuromedin B causes local vasodilation, increases vascular permeability and local hyperalgesia, thereby participating in neurogenic inflammation. Neuromedin B regulates appetite, body temperature, and behavioral responses to stress. Neuromedin B is also involved in regulating smooth muscle contraction and secretory function in the gastrointestinal tract.
  • HY-176150
    AMTG-DA1
    		Ligand
    AMTG-DA1 is a Gastrin-releasing peptide receptor (GRPR) ligand. AMTG-DA1 can be used in the study of cancer.